Hydroxyamine hydrochloride → HCID 136378420, compound

HRID 2379091Notes

Reaction equation

HRID 2379091 reaction equation
Cl.[NH2:2][OH:3].[OH:4][N:5]=[C:6]1[C:10](=O)[CH2:9][CH2:8][S:7]1(=[O:13])=[O:12]>O.CO>[OH:4][N:5]=[C:6]1[C:10](=[N:2][OH:3])[CH2:9][CH2:8][S:7]1(=[O:13])=[O:12]

Participants

5

Reactant 2

HCID 443297Hydroxyamine hydrochlorideHCID 86748225HCID 86748225, compound

Product 1

HCID 136378420HCID 136378420, compoundYield 50%

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

5.4 g (77 mmol) of hydroxylamine hydrochloride, dissolved in 15 ml of water, are added to a solution of 11.4 g (70 mmol) of 2-hydroxyimino-3-oxotetrahydrothiophene dioxide in 100 ml of methanol. After 2 hours at room temperature the batch is completely concentrated and the residue is recrystallised from ethanol. 6.2 g (50%) of 2,3-dihydroxyiminotetrahydrothiophene dioxide, m.p. 181° C., are obtained.

Workup

  1. concentrationAfter 2 hours at room temperature the batch is completely concentrated
  2. customthe residue is recrystallised from ethanol

Sources & evidence

ORD record
ord-1773dc2524774a9db6b650905db9435d
Source dataset
uspto-grants-1994_11
Patent number
US05360812

Reaction notes

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