Benzeneseleninic acid → HCID 18957927, compound

HRID 2379127Notes

Reaction equation

HRID 2379127 reaction equation
[C:1]1([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:6]=[CH:5][CH:4]=[C:3]([N:7]2[C:11]3[CH:12]=[CH:13][C:14]([CH2:16][OH:17])=[CH:15][C:10]=3[N:9]=[CH:8]2)[CH:2]=1.C1([Se](O)=O)C=CC=CC=1>C1(C)C=CC=CC=1>[C:1]1([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:6]=[CH:5][CH:4]=[C:3]([N:7]2[C:11]3[CH:12]=[CH:13][C:14]([CH:16]=[O:17])=[CH:15][C:10]=3[N:9]=[CH:8]2)[CH:2]=1

Participants

4

Reactant 2

HCID 23427Benzeneseleninic acidHCID 18957882HCID 18957882, compound

Product 1

HCID 18957927HCID 18957927, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
85 °C

Procedure

To a solution of 1-(3-biphenylyl)-5hydroxymethylbenzimidazole (61a) (0.2 g, 0.7 mmol) in toluene (3 ml) was added benzeneseleninic acid (0.19 g, 1 mmol). The reaction mixture was heated to 85° C. for 2 hours. After cooling, the product was filtered off and washed thoroughly with warm water. Yield: 80 mg, 0.27 mmol, 38%. mp 170°-172° C.

Workup

  1. temperatureAfter cooling
  2. filtrationthe product was filtered off
  3. washwashed thoroughly with warm water

Sources & evidence

ORD record
ord-60bfe7203d7c431c9ce614894706159d
Source dataset
uspto-grants-1994_11
Patent number
US05360809

Reaction notes

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