HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → 5-Ethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indol-1-one | HCID 15616323 | — |
| Product | 5-Ethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one | HCID 15616325 | — |
Reaction Steps
2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indol-1-one (931 mg) was treated with sodium hydride (60% dispersion in oil; 400 mg) and was then stirred with ethyl iodide (10% v/v solution in DMF; 4 ml) to give the title compound (758 mg), m.p. 203°-204.5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05360800 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-38485fcaeda3405eb00f49869b73ef45 |
| Source note | uspto-grants-1994_11 |