1-Propanol → HCID 18958047, compound

HRID 2379198Notes

Reaction equation

HRID 2379198 reaction equation
[F:1][C:2]1[C:7]([CH3:8])=[C:6]([F:9])[C:5]([F:10])=[C:4](F)[C:3]=1[F:12].[CH2:13]([OH:16])[CH2:14][CH3:15].[OH-].[Na+].[Br:19]N1C(=O)CCC1=O>O>[CH2:13]([O:16][C:4]1[C:5]([F:10])=[C:6]([F:9])[C:7]([CH2:8][Br:19])=[C:2]([F:1])[C:3]=1[F:12])[CH2:14][CH3:15]

Participants

6

Reactant 4

HCID 10311-PropanolHCID 14798Sodium HydroxideHCID 67184N-bromobutanimideHCID 69869Pentafluoromethylbenzene

Product 1

HCID 18958047HCID 18958047, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

This compound can be prepared by reacting pentafluorotoluene with propanol and sodium hydroxide in water, as described for the preparation of compound 37, followed by bromination with N-bromosuccinimide.

Workup

  1. customThis compound can be prepared

Sources & evidence

ORD record
ord-5f053417872d4ecc9e0368d4e8c7ef51
Source dataset
uspto-grants-1994_11
Patent number
US05360819

Reaction notes

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