Sodium Hydroxide → HCID 18958059, compound

HRID 2379199Notes

Reaction equation

HRID 2379199 reaction equation
FC1C(C)=C(F)C(F)=C(F)C=1F.[OH-].[Na+].[CH:15]([O:18][C:19]1[C:35]([F:36])=[C:34]([F:37])[C:22]([CH2:23]OC2C=CC(C(=O)C)=CC=2)=[C:21]([F:38])[C:20]=1[F:39])([CH3:17])[CH3:16].[Br:40]N1C(=O)CCC1=O>O.C(O)(C)C>[CH:15]([O:18][C:19]1[C:35]([F:36])=[C:34]([F:37])[C:22]([CH2:23][Br:40])=[C:21]([F:38])[C:20]=1[F:39])([CH3:17])[CH3:16]

Participants

7

Reactant 4

HCID 14798Sodium HydroxideHCID 67184N-bromobutanimideHCID 69869PentafluoromethylbenzeneHCID 131718761HCID 131718761, compound

Product 1

HCID 18958059HCID 18958059, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 3776IsopropanolSolvent

Procedure

This compound can be prepared by reacting pentafluorotoluene with isopropanol and sodium hydroxide in water, as described for the preparation of compound 38, followed by bromination with N-bromosuccinimide.

Workup

  1. customThis compound can be prepared

Sources & evidence

ORD record
ord-7882047c9aec405890a10e8f84708103
Source dataset
uspto-grants-1994_11
Patent number
US05360819

Reaction notes

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