反应详情

温度

50 °C

To a suspension of potassium glycolate (11.4 g) in acetonitrile (30 ml) KI (0.5 g) and acetoxymethyl bromide (19 g) were added. The mixture was stirred at 50° C. for 6 hours, and then cooled to room temperature. Diethyl ether was added and the solid filtered off. The solution was evaporated in vacuo and the oily residue was purified by column chromatography to yield 8 g of acetoxymethyl glycolate as a colourless oil.

1. additionwere added
2. temperaturecooled to room temperature
3. filtrationthe solid filtered off
4. customThe solution was evaporated in vacuo
5. customthe oily residue was purified by column chromatography