Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Bromomethyl acetate | HCID 68536 | — |
| Reactant | Potassium Glycolate | HCID 23668515 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | Acetoxymethyl glycolate | HCID 18958287 | 54.1% |
Reaction Steps
To a suspension of potassium glycolate (11.4 g) in acetonitrile (30 ml) KI (0.5 g) and acetoxymethyl bromide (19 g) were added. The mixture was stirred at 50° C. for 6 hours, and then cooled to room temperature. Diethyl ether was added and the solid filtered off. The solution was evaporated in vacuo and the oily residue was purified by column chromatography to yield 8 g of acetoxymethyl glycolate as a colourless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05360904 |
|---|
| Source dataset | uspto-grants-1994_11 |
|---|
| ORD ID | ord-d44cee9c70c04fc49d49546f1dd8d267 |
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| Source note | uspto-grants-1994_11 |
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