Hydrazine hydrate (1:1) → HCID 18958317, compound

Participants

Reaction Conditions

Reaction Steps

5 ml of ethanol solution of 1.02 g of hydrazine hydrate were added to 35 ml of ethanol solution of 4.36 g of t-butyl 4-[2-(phthalimido)ethyl]-2-nitrophenoxyacetate and heated under reflux for 2 hours at 100° C. in an argon stream. After cooling, the reaction mixture was filtered through celite, and the filtrate concentrated under reduced pressure. The yellow crystals of t-butyl 4-(2-aminoethyl)-2-nitrophenoxyacetate thus obtained were used in the next reaction without purification.

Provenance & Evidence