Potassium Hydroxide → HCID 10755357, compound

Participants

Reaction Steps

To a room temperature, stirred solution of potassium hydroxide (1.97 g, 0.035 mol) in absolute ethanol (280 mL) was added in one portion 2-dodecyl-2H-tetrazole-5-carboxylic acid, ethyl ester (8.7 g, 0.028 mol), and the mixture was stirred for 28 hours. A white precipitate formed. The solids were filtered off, washed with ethanol, and partitioned between ethyl acetate and 10% hydrochloric acid. The organic layer was washed with saturated sodium chloride, dried (MgSO4), and rotoevaporated to a white solid, yield 7.74 g (98%), mp=122°-124° C.

Provenance & Evidence