HRID2379595

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CN(C)CCOC(=O)c1cc(-c2ccccc2)c(=O)n2c1-c1ccccc1C2

HCID18957049

未命名化合物

PRODUCTS

生成物

结构：COC1CN(C(=O)c2cc(-c3ccccc3)c(=O)n3c2-c2c(Cl)cccc2C3)C1

HCID18957057

未命名化合物

PROCEDURE

实验过程

A method according to claim 14 wherein the compound is selected from methyl 4,6-dihydro-4-oxo-3-phenyl-4H-pyrido[2,1-a]isoindole-1-carboxylate; (dimethylcarbamoyl)methyl 4,6-dihydro-4-oxo-3-phenylpyrido-[2,1-a]isoindole-1-carboxylate; 2-(dimethylamino)ethyl-4,6-dihydro-4-oxo-3-phenylpyrido[2,1-a]isoindole-1-carboxylate; and methyl 10-fluoro-4,6-dihydro-4-oxo-3-phenylpyrido[2,1-a]isoindole-1-carboxylate; and methyl 10-chloro-4, 6-dihydro-4-oxo-3-phenylpyrido[2,1-a]isoindole-1-carboxylate.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d40f7295a25f4ca885ba5a239d69a262
来源数据集: uspto-grants-1994_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05362738
来源说明: uspto-grants-1994_11

反应 SMILES

O=C1N2CC3C(C2=C([C:15]([O:17][CH2:18][C:19](=O)[N:20]([CH3:22])C)=O)C=C1C1C=CC=CC=1)=CC=CC=3.CN(C)CCOC(C1C=C(C2C=CC=CC=2)C(=O)N2CC3C(=CC=CC=3)C=12)=O.FC1C=CC=C2C=1C1=C(C(OC)=O)C=C(C3C=CC=CC=3)C(=O)N1C2.[Cl:83][C:84]1[CH:85]=[CH:86][CH:87]=[C:88]2[C:92]=1[C:91]1=[C:93]([C:104](OC)=[O:105])[CH:94]=[C:95]([C:98]3[CH:103]=[CH:102][CH:101]=[CH:100][CH:99]=3)[C:96](=[O:97])[N:90]1[CH2:89]2>>[Cl:83][C:84]1[CH:85]=[CH:86][CH:87]=[C:88]2[C:92]=1[C:91]1=[C:93]([C:104]([N:20]3[CH2:19][CH:18]([O:17][CH3:15])[CH2:22]3)=[O:105])[CH:94]=[C:95]([C:98]3[CH:99]=[CH:100][CH:101]=[CH:102][CH:103]=3)[C:96](=[O:97])[N:90]1[CH2:89]2