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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2379595Generated: October 30, 2026

2-(Dimethylamino)ethyl 4,6-dihydro-4-oxo-3-phenylpyrido[2,1-a]isoindole-1-carboxylate → 1-[(10-Chloro-4,6-dihydro-4-oxo-3-phenylpyrido[2,1-a]isoindole-1-yl)carbonyl]-3-methoxyazetidine

https://huagongshe.com/reaction/2379595

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Dimethylamino)ethyl 4,6-dihydro-4-oxo-3-phenylpyrido[2,1-a]isoindole-1-carboxylateHCID 18957049—
ReactantMethyl 10-fluoro-4,6-dihydro-4-oxo-3-phenylpyrido[2,1-a]isoindole-1-carboxylateHCID 18957069—
Reactant(Dimethylcarbamoyl)methyl 4,6-dihydro-4-oxo-3-phenylpyrido-[2,1-a]isoindole-1-carboxylateHCID 18957074—
ReactantMethyl 10-chloro-4, 6-dihydro-4-oxo-3-phenylpyrido[2,1-a]isoindole-1-carboxylateHCID 18957091—
Product1-[(10-Chloro-4,6-dihydro-4-oxo-3-phenylpyrido[2,1-a]isoindole-1-yl)carbonyl]-3-methoxyazetidineHCID 18957057—

Reaction Steps

A method according to claim 14 wherein the compound is selected from methyl 4,6-dihydro-4-oxo-3-phenyl-4H-pyrido[2,1-a]isoindole-1-carboxylate; (dimethylcarbamoyl)methyl 4,6-dihydro-4-oxo-3-phenylpyrido-[2,1-a]isoindole-1-carboxylate; 2-(dimethylamino)ethyl-4,6-dihydro-4-oxo-3-phenylpyrido[2,1-a]isoindole-1-carboxylate; and methyl 10-fluoro-4,6-dihydro-4-oxo-3-phenylpyrido[2,1-a]isoindole-1-carboxylate; and methyl 10-chloro-4, 6-dihydro-4-oxo-3-phenylpyrido[2,1-a]isoindole-1-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05362738
Source datasetuspto-grants-1994_11
ORD IDord-d40f7295a25f4ca885ba5a239d69a262
Source noteuspto-grants-1994_11