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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2379634Generated: October 31, 2026

Dimethylamine → N-(4-dimethylamino-6-chloropyrimidin-5-yl)-cis-9-octadecenamide

https://huagongshe.com/reaction/2379634

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant5-Amino-4,6-dichloropyrimidineHCID 79434—
Reactant6-Chloro-N4,N4-dimethylpyrimidine-4,5-diamineHCID 768955—
ReactantOleoyl chlorideHCID 5364783—
ProductN-(4-dimethylamino-6-chloropyrimidin-5-yl)-cis-9-octadecenamideHCID 86748242—

Reaction Steps

5-Amino-4-(dimethyl)amino-6-chloropyrimidine (prepared by reacting commercially available 5-amino-4,6-dichloropyrimidine with excess dimethylamine) was coupled with oleoyl chloride according to the procedure described in Example 4 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05362878
Source datasetuspto-grants-1994_11
ORD IDord-fed3dd7bb72a42e9a1256dcb784c4cc7
Source noteuspto-grants-1994_11