Thionyl Chloride → 4-(4-Octyloxyphenyl)benzoyl chloride

HRID 2379652Notes

Reaction equation

HRID 2379652 reaction equation
[CH2:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([C:22]([OH:24])=O)=[CH:18][CH:17]=2)=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].S(Cl)([Cl:27])=O>>[CH2:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([C:22]([Cl:27])=[O:24])=[CH:18][CH:17]=2)=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 28025564'-(Octyloxy)-[1,1'-biphenyl]-4-carboxylic acid

Product 1

HCID 110784734-(4-Octyloxyphenyl)benzoyl chloride

Procedure

After 4-n-octyloxybiphenyl-4'-carboxylic acid (3.0 g) was heated under reflux together with an excessive amount of thionyl chloride for 6 hours, unaltered thionyl chloride was removed by distillation to give 4-n-octyloxybiphenyl-4'-carboxylic acid chloride.

Workup

  1. customunaltered thionyl chloride was removed by distillation

Sources & evidence

ORD record
ord-f183556b988f4894adc97b5487279cc8
Source dataset
uspto-grants-1994_11
Patent number
US05364561

Reaction notes

Loading…