Water → HCID 18955755, compound

Participants

Reaction Steps

Lithium aluminium hydride (5.3 mmols) was suspended in 38 ml of tetrahydrofuran, and 3.1 mmols of 4'-octyloxybiphenyl-4-carboxylic acid were slowly added. After stirring at room temperature for 2 hours, the reaction mixture was charged into a large amount of water, and extracted with dichloromethane. After the extract was dried over anhydrous sodium sulfate, the solvent was evaporated to obtain a final product. Since said product showed 1 spot in thin layer chromatography, it was used in the next step without purification. The yield was 95%.

Provenance & Evidence