HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 67820999, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | HCID 11045018 | HCID 11045018 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67820999 | HCID 67820999 | — |
Reaction Steps
A mixture of 4-(6-acetylaminomethylpyridin-2-yl)-2-thioureidothiazole (5.3 g) and methyl iodide (1.2 ml) in a solution of methanol (53 ml) and tetrahydrofuran (25 ml) was heated under reflux for 4.5 hours. The solvent was removed by concentration in vacuo and resulting residue was triturated with ethyl acetate to give 4-(6-acetylaminomethylpyridin-2-yl)-2-[(amino)(methylthio)methyleneamino]thiazole hydriodide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05364871 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-74120bf9e1fc494bbe420b37835d69a2 |
| Source note | uspto-grants-1994_11 |