HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 3-Pyridinecarboxamide, 5-acetyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Methyl 5-acetylpyridine-3-carboxylate | HCID 596459 | — |
| Product | 3-Pyridinecarboxamide, 5-acetyl- | HCID 22607388 | — |
Reaction Steps
A suspension of 5-acetyl-3-pyridinecarboxylic acid methyl ester (5.0 g) in 28% ammonia solution (30 ml) was stirred at room temperature for 2 hours. The resulting precipitate was collected by filtration to afford 3-acetyl-5-carbamoylpyridine (3.38 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05364871 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-d1cd05bb777243bc8999f460bbe1c019 |
| Source note | uspto-grants-1994_11 |