HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 178484928, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | HCID 54166508 | HCID 54166508 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178484928 | HCID 178484928 | — |
Reaction Steps
A mixture of 4-(6-acetylaminomethylpyridin-2-yl)-2-(3-methylthioureido)thiazole (1.5 g) and methyl iodide (0.45 ml) in a solution of methanol (15 ml) and tetrahydrofuran (8 ml) was heated under reflux for 9 hours. The solvent was removed by concentration and the residue was triturated with ethyl acetate to give 4-(6-acetylaminomethylpyridin-2-yl)-2-[(methylamino)(methylthio)methyleneamino]thiazole hydriodide (1.44 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05364871 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-e9c99baa233145b0bb09c80ed4471e12 |
| Source note | uspto-grants-1994_11 |