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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2379831Generated: November 1, 2026

Methyl iodide → HCID 86748245, compound

https://huagongshe.com/reaction/2379831

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantHCID 18956285HCID 18956285—
SolventMethanolHCID 887—
ProductHCID 86748245HCID 8674824564.7%

Reaction Steps

A suspension of 4-(6-propionylaminomethylpyridin-2-yl)-2-thioureidothiazole (14.67 g) and methyl iodide (7.77 g) in methanol (300 ml) was refluxed for 3 hours. The solvent was removed under reduced pressure. The residue was crystallized from ethyl acetate to afford 2-[(amino)(methylthio)methyleneamino]-4-(6-propionylaminomethylpyridin-2-yl)thiazole hydriodide (13.68 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05364871
Source datasetuspto-grants-1994_11
ORD IDord-e79c705d3df44ed18a8d52a10adf3f2a
Source noteuspto-grants-1994_11