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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2380054Generated: November 2, 2026

Methyl iodide → 1-(2,4-Difluorophenyl)-2-(pyridin-3-yl)propan-1-one

https://huagongshe.com/reaction/2380054

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
Reactant1-(2,4-Difluorophenyl)-2-(3-pyridinyl)-ethanoneHCID 18956524—
Product1-(2,4-Difluorophenyl)-2-(pyridin-3-yl)propan-1-oneHCID 1895654173.6%

Reaction Steps

Methylation of the product of part (i) (5.0 g) with iodomethane (7.60 g) according to the method of Example 11(ii) gave the title compound as an oil (3.90 g) which was used directly in the next stage.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05364938
Source datasetuspto-grants-1994_11
ORD IDord-5b211545779f4b3996fbdab503582604
Source noteuspto-grants-1994_11