HRID2380142
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
PROCEDURE
实验过程
Compound (10) (1.13 g, 1.47 mmol) was hydrogenated in CH3OH (150 mL) and 0.1N HCl (16.2 mL, 1.62 mmol) with 10% Pd-C (0.6 g) by the procedure used for [A]. Purification by Sephadex LH-20 column chromatography with 20% EtOH/toluene as the eluant produced 0.508 g (64%) of [A] as a colorless solid: NMR (CD3OD) δ 0.90 (t, 3H, J=6), 1.17-1.87 (m, 28H), 2.33-2.63 (m, 6H), 2.92 (t, 2H, J=6), 3.60 (t, 6H, J=6). Anal. (C25H51ClN4O6) C, H, N.
WORKUP
后处理
- customPurification by Sephadex
- customcolumn chromatography with 20% EtOH/toluene as the eluant produced 0.508 g (64%) of [A] as a colorless solid