Hydrochloric Acid → HCID 131717687, compound

Participants

Reaction Steps

To a solution of 7β-[2-(5-amino-1,2,4-thiadiazol-3-yl)-2-allyloxyiminoacetamido]-3-(4,5,6,7-tetrahydro-1-pyrazolo[1,5-a]pyrimidinio)methyl-3-cephem-4-carboxylate (syn isomer) (1 g) in water (3 ml) was added 2N hydrochloric acid (1 ml) at room temperature. The mixture was stirred at ambient temperature for 3 hours, and the resulting precipitate was collected by filtration to give 7β-[2-(5-amino-1,2,4-thiadiazol-3-yl)-2-allyloxyiminoacetamido]-3-(4,5,6,7-tetrahydro-1-pyrazolo[1,5-a]pyrimidinio)methyl-3-cephem-4-carboxylate hydrochloride (syn isomer) (202 mg) as crystals.

Provenance & Evidence