HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 238045Generated: October 25, 2026
Ammonia methanol → 5-Iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
https://huagongshe.com/reaction/238045
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia methanol | HCID 21705897 | — |
| Reactant | 4-chloro-5-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine | HCID 42609462 | — |
| Product | 5-Iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine | HCID 59424180 | — |
Reaction Steps
4-chloro-5-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine (90 mg, 0.31 mmol) was taken up in 7N NH3/MeOH and heated in a sealed tube at 110° C. overnight. Reaction was concentrated in vacuo to give a brown/off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08642604B2 |
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| Source dataset | uspto-grants-2014_02 |
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| ORD ID | ord-b53e7ab9cf454cf687ef75b9c23fbc95 |
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| Source note | uspto-grants-2014_02 |
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