Triethylamine → HCID 21469488, compound

HRID 2380456Notes

Reaction equation

HRID 2380456 reaction equation
[NH:1]1[CH:5]=[N:4][N:3]=[N:2]1.C([N:8]([CH2:11][CH3:12])CC)C.Br[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]>C(#N)C>[C:11]([CH:12]1[CH:17]([C:5]2[N:1]=[N:2][N:3]([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[N:4]=2)[CH2:16][CH2:15][CH2:14]1)#[N:8]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 89191-BromododecaneHCID 178418441HCID 178418441, compound

Product 1

HCID 21469488HCID 21469488, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The tetrazole (b) obtained above (11.0 g; 0.067 moles) was dissolved in acetonitrile (150 mL) containing one equivalent of triethylamine (6.8 g; 0.067 moles). The solution was heated to reflux followed by the addition of 1-bromo dodecane (16.8 g; 0.067 moles). Isolation of the 2-isomer was achieved employing the same conditions described for Example 11. Yield: 7.5 g; colorless liquid.

Workup

  1. temperatureThe solution was heated
  2. temperatureto reflux

Sources & evidence

ORD record
ord-bf0dcce0208c4a12816a4cfbde451457
Source dataset
uspto-grants-1994_11
Patent number
US05366987

Reaction notes

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