Diisopropylaniline → 5-dodecyl-alpha-(1-methylethyl)-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-2-acetamide
Reaction equation
[CH2:1]([C:13]1[N:14]=[N:15][N:16]([CH:18]([CH:22]([CH3:24])[CH3:23])[C:19]([OH:21])=O)[N:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(C1N=NN(CC(O)=O)N=1)CCCCCCCCC.[CH3:44][O:45][C:46]1[CH:52]=[C:51]([O:53][CH3:54])[CH:50]=[C:49]([O:55][CH3:56])[C:47]=1[NH2:48].C(C1C=CC=C(C(C)C)C=1N)(C)C>>[CH2:1]([C:13]1[N:14]=[N:15][N:16]([CH:18]([CH:22]([CH3:24])[CH3:23])[C:19]([NH:48][C:47]2[C:49]([O:55][CH3:56])=[CH:50][C:51]([O:53][CH3:54])=[CH:52][C:46]=2[O:45][CH3:44])=[O:21])[N:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]Participants
5
Procedure
When in the general procedure of Example 88 an appropriate amount of 5-dodecyl-α-(1-methylethyl)-2H-tetrazole-2-acetic acid was substituted for 5-decyl-2H-tetrazole-2-acetic acid and 2,4,6-trimethoxyaniline was substituted for 2,6-diisopropylaniline, the title compound was obtained, mp 135°-137° C.
Sources & evidence
- ORD record
- ord-1d6d10ad0e8b46c1a4fd5e7c2617eb6a
- Source dataset
- uspto-grants-1994_11
- Patent number
- US05366987
Reaction notes
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