Codeine phosphate hydrate → Codeine

Participants

Reaction Steps

95.0 g of codeine phosphate was dissolved in 950 ml of deionized water, and 359.9 g of Amberlite IRP 69 was added while stirring. The mixture was stirred for 1 hour. The codeine-resin complex was washed thoroughly in a Buchner funnel, and then dried in a fluidized bed drier for 1 hour at the inlet air temperature of 60° C. to yield a codeine-resin complex. B. Preparation of codeine-resin complex treated with polyethyleneglycol

Provenance & Evidence