Pilocarpine Hydrochloride → Pilocarpine

Participants

Reaction Steps

100.0 g of pilocarpine hydrochloride was dissolved in 900 ml of deionized water, and 300.0 g of Amberlite IRP69 was added while stirring. The mixture was stirred for 1 hour to yield a pilocarpine-resin complex. Then, the complex was treated with PEG and coated with the diffusion barrier material similarly as in Example 1 to obtain a coated pilocarpine-resin complex.

Provenance & Evidence