Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Chloride | HCID 5234 | — |
| Reactant | Borate | HCID 26574 | — |
| Reactant | L-Leucinamide, L-leucyl- | HCID 7015189 | — |
| Product | HCID 131718784 | HCID 131718784 | 60.3% |
Reaction Steps
2 ml 0.05 borate buffer, pH 9, containing 0.2M NaCl, 2 mMMal-Phe-OMe, 50 mM H-Leu-Leu-NH2 and 12 μM trypsinogen are agitated at 25° C. under pH control. The reaction is stopped as described in Example 1a. After 24 hours, the yield, analytically determined with HPLC, is 61% of theory. A parallel batch resulted, after 48 hours, in a yield of 60.3% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05369018 |
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| Source dataset | uspto-grants-1994_11 |
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| ORD ID | ord-46c7ed8af01c40b591ed6f968f3d659c |
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| Source note | uspto-grants-1994_11 |
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