反应详情

The starting material can be prepared, for example, as follows: Analogously to Example 4b) and using 2.64 g of N-butyl-N-(2'-cyanobiphenyl-4-ylmethyl)-amine and 2.68 g of ethylmalonic acid monoethyl ester monochloride as starting materials, there is obtained 2-ethoxycarbonylbutanoic acid N-butyl-N-(2'-cyano-biphenyl-4-ylmethyl)-amide that has an Rf value of 0.65 [CH2Cl2 /CH3OH (95:5)].