HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Butylaminomethyl-2-cyanobiphenyl → 2-ethoxycarbonylbutanoic acid N-butyl-N-(2'-cyano-biphenyl-4-ylmethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Butylaminomethyl-2-cyanobiphenyl | HCID 15338353 | — |
| Reactant | Ethylmalonic acid monoethyl ester monochloride | HCID 86748288 | — |
| Product | 2-ethoxycarbonylbutanoic acid N-butyl-N-(2'-cyano-biphenyl-4-ylmethyl)-amide | HCID 53852199 | — |
Reaction Steps
The starting material can be prepared, for example, as follows: Analogously to Example 4b) and using 2.64 g of N-butyl-N-(2'-cyanobiphenyl-4-ylmethyl)-amine and 2.68 g of ethylmalonic acid monoethyl ester monochloride as starting materials, there is obtained 2-ethoxycarbonylbutanoic acid N-butyl-N-(2'-cyano-biphenyl-4-ylmethyl)-amide that has an Rf value of 0.65 [CH2Cl2 /CH3OH (95:5)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05369110 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-ac99490fd0024110b712c18a14666f45 |
| Source note | uspto-grants-1994_11 |