HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 2-Hydrazinyl-5-phenyl-1,3,4-thiadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 2-Chloro-5-phenyl-1,3,4-thiadiazole | HCID 253145 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 2-Hydrazinyl-5-phenyl-1,3,4-thiadiazole | HCID 253148 | — |
Reaction Steps
A solution of the 2-Chloro-5-phenyl-[1,3,4]thiadiazole (2 mmol) and hydrazine hydrate (6 mmol, 3 eq) in iPrOH (10 mL) was heated at reflux overnight. The solvent was evaporated, water was added, and the product was isolated by filtration (110 mg, 57%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08257931B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-d89b84f4032c47d3acc9c588e3c7b024 |
| Source note | uspto-grants-2012_09 |