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HRID2380757

反应详情

EQUATION

反应方程式

HRID 2380757 的结构方程式

REACTANTS

反应物

2
结构：NN.O
HCID24654

Hydrazine hydrate (1:1)

H6N2O

结构：Clc1nnc(-c2ccccc2)s1
HCID253145

2-Chloro-5-phenyl-1,3,4-thiadiazole

C8H5ClN2S

PRODUCTS

生成物

1
结构：NNc1nnc(-c2ccccc2)s1
HCID253148

2-hydrazinyl-5-phenyl-1,3,4-thiadiazole

C8H8N4S

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)O
溶剂HCID3776

Isopropanol

C3H8O

PROCEDURE

实验过程

A solution of the 2-Chloro-5-phenyl-[1,3,4]thiadiazole (2 mmol) and hydrazine hydrate (6 mmol, 3 eq) in iPrOH (10 mL) was heated at reflux overnight. The solvent was evaporated, water was added, and the product was isolated by filtration (110 mg, 57%).

WORKUP

后处理

  1. temperatureat reflux overnight
  2. customThe solvent was evaporated
  3. additionwater was added
  4. customthe product was isolated by filtration (110 mg, 57%)