HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57489618, compound → Benzyl 4-(4-aminophenyl)piperazine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57489618 | HCID 57489618 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Benzyl 4-(4-aminophenyl)piperazine-1-carboxylate | HCID 57489619 | — |
Reaction Steps
11.28 g benzyl 4-(4-nitro-phenyl)-piperazine-1-carboxylate are dissolved in 500 mL MeOH and combined with 1 g Raney nickel. The mixture is hydrogenated for 18 h at 5 bar H2 pressure. Then the mixture is filtered to remove the catalyst, 70 mL of 1 N aqueous hydrochloric acid are added and the solvent is eliminated in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08258129B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-e35ae6c390ba43249dda4ccd9025cb33 |
| Source note | uspto-grants-2012_09 |