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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2380839Generated: October 26, 2026

N-((1,1-dimethylethoxy)carbonyl)-2-methyl-alanine → tert-Butyl 1-(2-(3,5-difluoropyridin-2-yl)hydrazinyl)-2-methyl-1-oxopropan-2-ylcarbamate

https://huagongshe.com/reaction/2380839

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-((1,1-dimethylethoxy)carbonyl)-2-methyl-alanineHCID 2733845—
Reactant3,5-Difluoro-2-hydrazinylpyridineHCID 21102305—
Producttert-Butyl 1-(2-(3,5-difluoropyridin-2-yl)hydrazinyl)-2-methyl-1-oxopropan-2-ylcarbamateHCID 68714361—

Reaction Steps

This compound was prepared (66%) from 3,5-difluoro-2-hydrazinopyridine and N-(tert-butoxycarbonyl)-2-methylalanine following the experimental procedure described for the synthesis of Intermediate 21, step a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08258122B2
Source datasetuspto-grants-2012_09
ORD IDord-f473e0b50a9e41cba1627851fb3bb644
Source noteuspto-grants-2012_09