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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2381008Generated: October 26, 2026

1,4-Benzenediamine, N,N,N'-trimethyl- → (2-Chloro-quinazolin-4-yl)-(4-dimethylaminophenyl)-methylamine

https://huagongshe.com/reaction/2381008

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Benzenediamine, N,N,N'-trimethyl-HCID 591595—
Reactant2,4-Dichloro-6-nitroquinazolineHCID 12703366—
Product(2-Chloro-quinazolin-4-yl)-(4-dimethylaminophenyl)-methylamineHCID 11688214—

Reaction Steps

The title compound was prepared from 2,4-dichloro-6-nitro-quinazoline and N1,N1,N4-trimethylbenzene-1,4-diamine by a procedure similar to example 44. 1H NMR (CDCl3): 7.71 (m, 1H), 7.51-7.56 (m, 1H), 7.07 (m, 2H), 6.99 (m, 2H), 6.71 (m, 2H), 3.59 (s, 3H), 3.01 (s, 6H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08258145B2
Source datasetuspto-grants-2012_09
ORD IDord-d7bcdd348dd34b9bb534c4da71714c7e
Source noteuspto-grants-2012_09