HRID2381018

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6328

Methyl iodide

CH3I

HCID22692737

2-Chloro-N-(2,5-dimethoxyphenyl)quinazolin-4-amine

C16H14ClN3O2

PRODUCTS

生成物

结构：COc1ccc(OC)c(N(C)c2nc(Cl)nc3ccccc23)c1

HCID11255967

(2-Chloro-quinazolin-4-yl)-(2,5-dimethoxy-phenyl)-methyl-amine

C17H16ClN3O2

PROCEDURE

实验过程

The title compound was prepared from (2-chloro-quinazolin-4-yl)-(2,5-dimethoxy-phenyl)-amine and methyl iodide by a procedure similar to example 7 (78% yield). 1H NMR (CDCl3): 7.72-7.75 (m, 1H), 7.56 (ddd, J=8.4, 5.7 and 2.1 Hz, 1H), 6.98-7.00 (m, 2H), 6.92-6.92 (m, 2H), 6.78-6.79 (m, 1H), 3.75 (s, 3H), 3.58 (s, 3H), 3.56 (s, 3H).