HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 2-(2-Formyl-3-methylphenoxy)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Potassium Persulfate | HCID 24412 | — |
| Reactant | 2-(2,3-Dimethylphenoxy)acetamide | HCID 15943030 | — |
| Catalyst | Copper sulfate pentahydrate | HCID 24463 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(2-Formyl-3-methylphenoxy)acetamide | HCID 58387820 | 11% |
Reaction Steps
12.0 g of 7, 50.82 g of potassium peroxodisulfate and 17.05 g of copper(II) sulfate pentahydrate are dissolved in a solvent mixture comprising 250 ml of MeCN and 250 ml of water, and the mixture is subsequently stirred under reflux for 2 h. The mixture is then subjected to conventional work-up, giving 1.38 g (11%) of 2-(2-formyl-3-methylphenoxy)acetamide 8; MS-EI (M+)=193.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08258151B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-c2c6ba377f6f42208392baa427c654ab |
| Source note | uspto-grants-2012_09 |