反应详情

12.0 g of 7, 50.82 g of potassium peroxodisulfate and 17.05 g of copper(II) sulfate pentahydrate are dissolved in a solvent mixture comprising 250 ml of MeCN and 250 ml of water, and the mixture is subsequently stirred under reflux for 2 h. The mixture is then subjected to conventional work-up, giving 1.38 g (11%) of 2-(2-formyl-3-methylphenoxy)acetamide 8; MS-EI (M+)=193.

1. temperatureunder reflux for 2 h