Perchloric Acid → HCID 24854990, compound

Participants

Reaction Steps

3.2 0.177 g of 2-amino-5-fluoropyridine 4 and 0.288 g of the aldehyde 10 are dissolved successively in 30 ml of ethanol at RT under an inert gas. 0.205 g of 2,6-dimethylphenylisocyanide 5 is then added, 64.1 μl of 70% perchloric acid are added dropwise, and the mixture is stirred at RT for a further 20 h. The mixture is subsequently subjected to conventional work-up, giving 0.286 g (43%) of “A3”; m.p. 186-187°; MS-EI (M+)=438.

Provenance & Evidence