Pentanoic Acid → 6-(4-{4-[2-(4-Pentanoylpiperazin-1-yl)ethoxy]phenyl}piperidin-1-yl)-3-(trifluoromethyl)-7,8-dihydro[1,2,4]triazolo[4,3-b]pyridazine

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Pentanoic Acid	HCID 7991	—
Edukt	6-[4-[4-[2-(Piperazin-1-yl)ethoxy]phenyl]piperidin-1-yl]-3-(trifluoromethyl)-7,8-dihydro-[1,2,4]triazolo[4,3-b]pyridazine	HCID 68503084	—
Produkt	6-(4-{4-[2-(4-Pentanoylpiperazin-1-yl)ethoxy]phenyl}piperidin-1-yl)-3-(trifluoromethyl)-7,8-dihydro[1,2,4]triazolo[4,3-b]pyridazine	HCID 46893980	36%

Reaktionsschritte

Obtained in 36% yield by an analogous method to Example 4.1, starting from 6-[4-[4-[2-(piperazin-1-yl)ethoxy]phenyl]piperidin-1-yl]-3-(trifluoromethyl)-7,8-dihydro-[1,2,4]triazolo[4,3-b]pyridazine and pentanoic acid.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08258140B2
Quelldatensatz	uspto-grants-2012_09
ORD ID	ord-31e782ba22264fb6a791c874f28682a7
Quellennotiz	uspto-grants-2012_09