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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2381187Generated: November 2, 2026

4,4-Dimethylpentanoic acid → HCID 51001572, compound

https://huagongshe.com/reaction/2381187

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,4-Dimethylpentanoic acidHCID 14237—
ReactantN-[4-(Trifluoromethoxy)phenyl]piperidine-4-carboxamideHCID 18072435—
ProductHCID 51001572HCID 5100157289%

Reaction Steps

This material was prepared in analogy to example 8 step C) from piperidine-4-carboxylic acid (4-trifluoromethoxy-phenyl)-amide (0.144 g) and 4,4-dimethyl-pentanoic acid (0.065 g) to give the desired 1-(4,4-dimethyl-pentanoyl)-piperidine-4-carboxylic acid (4-trifluoromethoxy-phenyl)-amide (0.178 g) as an off-white solid. MS (ESI): 401.25 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08258158B2
Source datasetuspto-grants-2012_09
ORD IDord-bd081acb33be4bc0b128fdf220e608a8
Source noteuspto-grants-2012_09