HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86636612, compound → HCID 44467020, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86636612 | HCID 86636612 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 44467020 | HCID 44467020 | 74.4% |
Reaction Steps
A solution of tert-butyl (1-(2-(4-(4-acetylpiperazin-1-yl)phenylamino)-5-fluoropyrimidin-4-yl)piperidin-2-yl)methylcarbamate (56 mg, 0.11 mmol) in TFA (3 mL) was stirred at room temperature for 60 min. TFA was removed in vacuo. The residue was purified by HPLC to give the titled compound (35 mg) MS 428.4 (M+H); UV 213.8, 258.8 nm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08258144B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-5c5643205cd046bab1b0949b9cdb9b74 |
| Source note | uspto-grants-2012_09 |