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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2381626Generated: November 2, 2026

HCID 86636612, compound → HCID 44467020, compound

https://huagongshe.com/reaction/2381626

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86636612HCID 86636612—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 44467020HCID 4446702074.4%

Reaction Steps

A solution of tert-butyl (1-(2-(4-(4-acetylpiperazin-1-yl)phenylamino)-5-fluoropyrimidin-4-yl)piperidin-2-yl)methylcarbamate (56 mg, 0.11 mmol) in TFA (3 mL) was stirred at room temperature for 60 min. TFA was removed in vacuo. The residue was purified by HPLC to give the titled compound (35 mg) MS 428.4 (M+H); UV 213.8, 258.8 nm.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08258144B2
Source datasetuspto-grants-2012_09
ORD IDord-5c5643205cd046bab1b0949b9cdb9b74
Source noteuspto-grants-2012_09