Ethyl orthoformate → HCID 178424340, compound

HRID 2382149Notes

Reaction equation

HRID 2382149 reaction equation
[ClH:1].[CH:2]1[C:15]2[C:6](=[N:7][C:8]([NH:16][NH:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=3[CH3:24])=[C:9]3[C:14]=2[CH:13]=[CH:12][CH:11]=[CH:10]3)[CH:5]=[CH:4][CH:3]=1.[CH:25](OCC)(OCC)OCC>>[Cl-:1].[C:19]1([CH3:24])[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=1[N+:17]1[N:16]=[CH:8][N:7]2[C:25]=1[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][C:14]=1[C:15]1[CH:2]=[CH:3][CH:4]=[CH:5][C:6]2=1

Participants

3

Reactant 2

HCID 31214Ethyl orthoformateHCID 67128317N-Phenanthridin-6-yl-N'-o-tolylhydrazine hydrochloride

Product 1

HCID 178424340HCID 178424340, compound

Procedure

A suspension of N-phenanthridin-6-yl-N′-o-tolylhydrazine hydrochloride (9.0 g, 27 mmol) in triethyl orthoformate (360 ml) is stirred under reflux under argon for 17 h. After cooling to room temperature, the precipitate is filtered off and washed with triethyl orthoformate and cold acetone. Yield: 8.2 g (88%).

Workup

  1. temperatureunder reflux under argon for 17 h
  2. filtrationthe precipitate is filtered off
  3. washwashed with triethyl orthoformate and cold acetone

Sources & evidence

ORD record
ord-7f88bf9d27db475fb9f264afa88ff6da
Source dataset
uspto-grants-2012_09
Patent number
US08258297B2

Reaction notes

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