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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2382162Generated: October 31, 2026

HCID 58869858, compound → HCID 11673374, compound

https://huagongshe.com/reaction/2382162

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 58869858HCID 58869858—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 11673374HCID 11673374—

Reaction Steps

A mixture of intermediate (1) (0.0102 mol) in THF (50 ml) was hydrogenated with palladium on carbon (10%; 0.3 g) as a catalyst for 30 minutes at a temperature of 50° C. After uptake of hydrogen (1 equivalent), the catalyst was filtered off and the filtrate was evaporated, yielding (5′-amino-3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl-4-yl)-acetic acid ethyl ester (intermediate 2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08258304B2
Source datasetuspto-grants-2012_09
ORD IDord-975e09f4dc974a49b59ba613a9722e95
Source noteuspto-grants-2012_09