HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 68776068, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 67128323 | HCID 67128323 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68776068 | HCID 68776068 | — |
Reaction Steps
To the above ester in DCM (26 mL) was added TFA (8.7 mL) and stirred at room temperature. After 3 hours, the reaction mixture was concentrated and treated with Et2O. The solid formed was then filtered and washed with ether and dried to give 4-(2-(2-oxopyrrolidin-1-yl)propanamido)benzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08258316B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-1ed0b8dbe105435ab51bc1546ce2af95 |
| Source note | uspto-grants-2012_09 |