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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2382341Generated: November 1, 2026

HCID 21308699, compound → HCID 86647542, compound

https://huagongshe.com/reaction/2382341

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21308699HCID 21308699—
SolventTrifluoroacetic acid waterHCID 22392675—
ProductHCID 86647542HCID 86647542—

Reaction Steps

A solution of (3aS,4S,6R,6aR)-6-[2-Chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid ethylamide (Step D1) in TFA/water (2:1) is stirred at RT overnight. The reaction mixture is concentrated in vacuo to afford the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08258141B2
Source datasetuspto-grants-2012_09
ORD IDord-b548885b1a8e469d85d981858f3a96c6
Source noteuspto-grants-2012_09