HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21308699, compound → HCID 86647542, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21308699 | HCID 21308699 | — |
| Solvent | Trifluoroacetic acid water | HCID 22392675 | — |
| Product | HCID 86647542 | HCID 86647542 | — |
Reaction Steps
A solution of (3aS,4S,6R,6aR)-6-[2-Chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid ethylamide (Step D1) in TFA/water (2:1) is stirred at RT overnight. The reaction mixture is concentrated in vacuo to afford the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08258141B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-b548885b1a8e469d85d981858f3a96c6 |
| Source note | uspto-grants-2012_09 |