Phenyl chloroformate → HCID 58288710, compound

HRID 2382574Notes

Reaction equation

[C:1]([C:5]1[CH:10]=[C:9]([OH:11])[C:8]([OH:12])=[C:7]([CH3:13])[CH:6]=1)([CH3:4])([CH3:3])[CH3:2].Cl[C:15]([O:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[O:16]>>[C:15](=[O:16])([O:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[O:11][C:9]1[CH:10]=[C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[CH:6]=[C:7]([CH3:13])[C:8]=1[O:12][C:15](=[O:16])[O:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

Reactant 2

HCID 15891Phenyl chloroformate

HCID 751735-tert-Butyl-3-methylpyrocatechol

Product 1

HCID 58288710HCID 58288710, compoundYield 75.2%

Procedure

Prepared from 5-tert-butyl-3-methylbenzene-1,2-diol and phenyl chloroformate; purified by recrystallization from ethanol to yield a while solid (75.2%); 1H NMR (500 MHz, CDCl3, ppm): δ 7.35-7.38 (m, 4H), 7.23-7.28 (m, 7H), 7.16-7.17 (m, 1H), 2.36 (s, 3H), 1.32 (s, 9H).

Workup

custompurified by recrystallization from ethanol

Sources & evidence

ORD record: ord-0452d21693b3499889a21b45a4ca42dc
Source dataset: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08263520B2

Reaction notes

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