HCID 58748417, compound → HCID 58748479, compound

HRID 2382647Notes

Reaction equation

HRID 2382647 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([CH3:15])=[C:11]([N+:16]([O-])=O)[CH:10]=2)=[CH:5][CH:4]=1>[Pd].CO>[NH2:16][C:11]1[CH:10]=[C:9]([C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)[CH:14]=[CH:13][C:12]=1[CH3:15]

Participants

4

Reactant 1

HCID 58748417HCID 58748417, compound

Product 1

HCID 58748479HCID 58748479, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A suspension of 4′-methoxy-4-methyl-3-nitrobiphenyl (630 mg, 2.95 mmol) and 10% palladium on charcoal (63 mg, 0.059 mmol) in methanol (6 mL) is stirred under hydrogen atmosphere for 12 hours. Palladium catalyst is removed by filtration and the resulting solution is evaporated in vacuo to afford the title compound.

Workup

  1. customPalladium catalyst is removed by filtration
  2. customthe resulting solution is evaporated in vacuo

Sources & evidence

ORD record
ord-770ce03128dd47f59d11f268093dbb84
Source dataset
uspto-grants-2012_09
Patent number
US08263590B2

Reaction notes

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