反应详情

Trifluoroacetic acid (30 ml) was added to a solution of (2-phenyl-imidazo[1,2-a]pyridin-7-yl)-carbamic acid tert-butyl ester (4.81 g, 15 mmol) in CH2Cl2 (30 ml), and the mixture was stirred at r.t. overnight. The mixture was then washed (water, 2×50 ml), dried (Na2SO4), and the solvent was evaporated. The title compound (2.25 g, 73%) was obtained from the residue by column chromatography (silica gel, CH2Cl2: MeOH=100:0-60:40). MS (m/e)=210.1 [M+H+].

1. washThe mixture was then washed (water, 2×50 ml)
2. dry with materialdried (Na2SO4)
3. customthe solvent was evaporated