Hydrochloric Acid → HCID 25212518, compound

Participants

Reaction Steps

The title compound was prepared following procedure described for intermediate B1, but starting from 6-bromo[1,2,4]triazolo[1,5-a]pyridin-2-amine ((A5), 5.0 g; 23.5 mmol; 1.0 eq.) and nicotinoyl chloride hydrochloride (5.01 g; 28.2 mmol; 1.2 eq.) as a light yellow solid (6.30 g; 84%). HPLC, Rt: 1.32 min. (purity 99.6%). LC/MS, M+(ESI): 317.9. CHN analysis: [C12H8N5OBr.1.0 HCl.1.0 H20] Corrected: C, 38.68%; H, 2.98%; N 18.80%. Found: C, 38.76%; H, 3.11%; N, 18.66%.

Provenance & Evidence