3-Pyridinecarbonyl chloride, hydrochloride (1:1) → HCID 25212520, compound

Participants

Reaction Steps

The title compound was prepared following procedure described for intermediate B1, but starting from 5-chloro-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-amine ((A7), 2.72 g; 11.5 mmol; 1.0 eq.) and nicotinoyl chloride hydrochloride (2.46 g; 13.8 mmol; 1.2 eq.) as a greenish solid (1.42 g; 36%). HPLC, Rt: 2.16 min. (purity 100%). LC/MS, M+(ESI): 342.2, M−(ESI): 340.2.

Provenance & Evidence